業績紹介

主要論文リスト

中熊秀喜
園木孝志
花岡伸佳

年報

年報を御覧頂くためには,Adobe Readerが必要となります。パソコンにインストールされていない方は左のアイコンをクリックしてダウンロードしてください。

中熊秀喜

Kojima K, Konopleva M, Tsao T, Nakakuma H, Andreeff M: Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia. Blood. 2008;112:2886-2895.
Kojima K, Shimanuki M, Shikami M, Samudio IJ, Ruvolo V, Corn P, Hanaoka N, Konopleva M, Andreeff M, Nakakuma H：The dual PI3 kinase/mTOR inhibitor PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mitochondrial apoptosis in p53 wild-type AML. Leukemia, 2008;22:1728-1736.
Kawaguchi T, Nakakuma H：New insights into molecular pathogenesis of bone marrow failure in paroxysmal nocturnal hemoglobinuria. Int J Hematol 86(1):27-32,2007
Hanaoka N, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakuma H.：Immunoselection by natural killer cells of PIGA mutant cells missing stress-inducible ULBP. Blood 1;107(3):1184-91. 2006
Omine M, Kinoshita T, Nakakuma H, Maciejewski JP, Parker CJ, Socie G.：Paroxysmal nocturnal hemoglobinuria.　Int J Hematol 82(5):417-21. 2005
Nishimura J, Kanakura Y, Ware RE, Shichishima T, Nakakuma H, Ninomiya H, Decastro CM, Hall S, Kanamaru A, Sullivan KM, Mizoguchi H, Omine M, Kinoshita T, Rosse WF.: Clinical course and flow cytometric analysis of paroxysmal nocturnal hemoglobinuria in the United States and Japan. Medicine 83(3):193-207. 2005
Murakami Y, Siripanyapinyo U, Hong Y, Kang JY, Ishihara S, Nakakuma H, Maeda Y, Kinoshita T.: PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor. Mol Biol Cell 14(10):4285-95. 2003
Nakakuma H, Kawaguchi T.: Pathogenesis of selective expansion of PNH clones. Int J Hematol 77(2):121-4. 2003
Nagakura S, Ishihara S, Dunn DE, Nishimura J, Kawaguchi T, Horikawa K, Hidaka M, Kagimoto T, Eto N, Mitsuya H, Kinoshita T, Young NS, Nakakuma H.: Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro. Blood 1;100(3):1031-7. 2002
Horikawa K, Kawaguchi T, Ishihara S, Nagakura S, Hidaka M, Kagimoto T, Mitsuya H, Nakakuma H.: Frequent detection of T cells with mutations of the hypoxanthine-guanine phosphoribosyl transferase gene in patients with paroxysmal nocturnal hemoglobinuria. Blood 1;99(1):24-9. 2002
Ishihara S, Nakakuma H, Kawaguchi T, Nagakura S, Horikawa K, Hidaka M, Asou N, Mitsuya H.: Two cases showing clonal progression with full evolution from aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome to myelodysplastic syndromes and leukemia. Int J Hematol 72(2):206-9. 2002
Li K, Kawaguchi T, Ishihara S, Horikawa K, Hidaka M, Sakaguchi M, Tsuruzaki R, Kawakita M, Kagimoto T, Mitsuya H, Nakakuma H.: Rarity of microsatellite alterations in patients with paroxysmal nocturnal haemoglobinuria. Eur J Haematol 64(6):430-2. 2000
Ishihara S, Horikawa K, Kawaguchi T, Ke L, Hidaka M, Nagakura S, Mitsuya H, Sendo F, Nakakuma H.: 3H9, a monoclonal antibody capable of discriminating neutrophilic from basophilic and eosinophilic granulocytes. Eur J Haematol 64(4):275-6. 2000
Kawaguchi T, Koga S, Hongo H, Komiyama Y, Li K, Ishihara S, Horikawa K, Hidaka M, Mitsuya H, Nakakuma H.: A novel type of factor XI deficiency showing compound genetic abnormalities: a nonsense mutation and an impaired transcription. Int J Hematol 71(1):84-9.2000
Hidaka M, Nakakuma H.: [Catalase (CAT)] Nippon Rinsho. 57 Suppl:496-8. 1999
Nagakura S, Nakakuma H.: [Plasma protein] Nippon Rinsho. 57 Suppl:183-7. 1999
Iwanaga M, Furukawa K, Amenomori T, Mori H, Nakamura H, Fuchigami K, Kamihira S, Nakakuma H, Tomonaga M.: Paroxysmal nocturnal haemoglobinuria clones in patients with myelodysplastic syndromes. Br J Haematol. 102(2):465-74. 1998
Nakakuma H, Nagakura S, Kawaguchi T, Horikawa K, Iwamoto N, Kagimoto T, Takatsuki K.: Markedly high plasma erythropoietin and granulocyte-colony stimulating factor levels in patients with paroxysmal nocturnal hemoglobinuria.Int J Hematol. 66(4):451-7. 1997
Horikawa K, Nakakuma H, Kawaguchi T, Iwamoto N, Nagakura S, Kagimoto T, Takatsuki K.: Apoptosis resistance of blood cells from patients with paroxysmal nocturnal hemoglobinuria, aplastic anemia, and myelodysplastic syndrome. Blood. 1;90(7):2716-22. 1997
Nagakura S, Kawaguchi T, Fujimoto K, Horikawa K, Iwamoto N, Nakakuma H.: Sequential development of myelodysplasia and paroxysmal nocturnal hemoglobinuria in a patient with preceding aplastic anemia. Int J Hematol. 65(2):187-9. 1997
Kagimoto T, Nakakuma H, Hata H, Hidaka M, Horikawa K, Kawaguti T, Nagakura S, Iwamoto N, Shirono K, Kawano F, Takatsuki K.: Differential glycosylation of Bence Jones protein and kidney impairment in patients with plasma cell dyscrasia. J Lab Clin Med. 129(2):217-23. 1997
Nakakuma H, Kawaguchi T.: Paroxysmal nocturnal hemoglobinuria (PNH): mechanism of intravascular hemolysis. Crit Rev Oncol Hematol. 24(3):213-29. 1996
Kawaguchi T, Nakakuma H.: [Glycosylphosphatidylinositol-anchored proteins with complement-regulatory activity on erythrocytes] Nippon Rinsho. 54(9):2370-5. 1996
Nakakuma H.: Mechanism of intravascular hemolysis in paroxysmal nocturnal hemoglobinuria (PNH). Am J Hematol. 53(1):22-9. 1996
Iwamoto N, Kawaguchi T, Horikawa K, Nagakura S, Kagimoto T, Suda T, Takatsuki K, Nakakuma H.: Preferential hematopoiesis by paroxysmal nocturnal hemoglobinuria clone engrafted in SCID mice. Blood. 87(12):4944-8. 1996
Horikawa K, Fujisao S, Iwamoto N, Nagakura S, Kawaguchi T, Nishimura Y, Takatsuki K, Nakakuma H.: Cyclosporin-responsive pancytopenia and HLA class II alleles of a patient with paroxysmal nocturnal hemoglobinuria. Int J Hematol. 63(2):165-6. 1996
Nakakuma H, Kawaguchi T, Horikawa K, Hidaka M, Nagakura S, Iwamoto N, Kagimoto T, Takatsuki K.: Proposal for a classification of the clinical stages of paroxysmal nocturnal hemoglobinuria. Blood. 86(5):2051-2. 1995
Iwamoto N, Nagakura S, Kawaguchi T, Horikawa K, Takatsuki K, Nakakuma H.: T-lymphoblastic lymphoma/leukemia cells negative for CD52 and CD59. Int J Hematol. 62(1):55-7. 1995
Nakakuma H, Hidaka M, Nagakura S, Nishimura Y, Iwamoto N, Horikawa K, Kawaguchi T, Kagimoto T, Takatsuki K.: Expression of cryptantigen Th on paroxysmal nocturnal hemoglobinuria erythrocytes in association with a hemolytic exacerbation. J Clin Invest. 96(1):201-6. 1995
Nakakuma H, Nagakura S, Iwamoto N, Horikawa K, Kawaguchi T, Takatsuki K.
Migration to an inflammatory site in vivo of paroxysmal nocturnal hemoglobinuria lymphocytes.: Int J Hematol. 61(4):223-5. 1995
Iwamoto N, Kawaguchi T, Nagakura S, Hidaka M, Horikawa K, Kagimoto T, Takatsuki K, Nakakuma H.: Markedly high population of affected reticulocytes negative for decay-accelerating factor and CD59 in paroxysmal nocturnal hemoglobinuria. Blood. 85(8):2228-32. 1995
Nakakuma H, Nagakura S, Iwamoto N, Kawaguchi T, Hidaka M, Horikawa K, Kagimoto T, Shido T, Takatsuki K.: Paroxysmal nocturnal hemoglobinuria clone in bone marrow of patients with pancytopenia. Blood. 85(5):1371-6. 1995
Horikawa K, Nakakuma H. : [Plasma proteins] Nippon Rinsho. 53 Su Pt 1:159-62. 1995
Iwamoto N, Nakakuma H, Ota N, Shimokado H, Takatsuki K.: Ascorbic acid-induced hemolysis of paroxysmal nocturnal hemoglobinuria erythrocytes. Am J Hematol. 47(4):337-8. 1994
Nakakuma H, Nagakura S, Kawaguchi T, Iwamoto N, Hidaka M, Horikawa K, Kagimoto T, Tsuruzaki R, Takatsuki K.: Persistence of affected T lymphocytes in long-term clinical remission in paroxysmal nocturnal hemoglobinuria. Blood. 84(11):3925-8. 1994
Iwamoto N, Kawaguchi T, Takatsuki K, Nakakuma H, Koyama W.: Positivity of the sugar-water test in the screening for paroxysmal nocturnal hemoglobinuria. Blood. 84(4):1349. 1994
Mori S, Kawaguchi T, Kakinuma H, Fuji-i H, Koga S, Suzushima H, Tsuji N, Nakakuma H, Takatsuki K.: Alcaptonuria: a case complicated with valvular heart disease and immunodeficiency. Intern Med. 33(8):512-6. 1994
Nakakuma H, Nagakura S, Horikawa K, Hidaka M, Kawaguchi T, Iwamoto N, Sanada I, Kagimoto T, Takatsuki K.: Interleukin-2-dependent T-cell lines established from paroxysmal nocturnal hemoglobinuria patients. Blood. 84(1):309-14. 1994
Masuda T, Yonemura Y, Fujimoto K, Hidaka M, Nagakura S, Nakakuma H, Hata H, Sanada I, Kawakita M, Takatsuki K.: Establishment of a human T-cell line with deficient surface expression of glycosylphosphatidylinositol (GPI)-anchored proteins from a patient with paroxysmal nocturnal haemoglobinuria. Br J Haematol. 87(1):24-30. 1994
Iwamoto N, Kawaguchi T, Horikawa K, Nagakura S, Hidaka M, Kagimoto T, Takatsuki K, Nakakuma H.: Haemolysis induced by ascorbic acid in paroxysmal nocturnal haemoglobinuria. Lancet. 343(8893):357. 1994
Nakakuma H.: [Paroxysmal nocturnal hemoglobinuria--pathophysiological implication of altered glycosylation] Seikagaku. 66(2):137-49. 1994
Nagakura S, Kawaguchi T, Horikawa K, Hidaka M, Iwamoto N, Takatsuki K, Nakakuma H, Kagimoto T.: A deficiency in CDw52 (CAMPATH-1 antigen) of paroxysmal nocturnal hemoglobinuria lymphocytes. Blood. 82(12):3790-2. 1993
Nakakuma H.: [Paroxysmal nocturnal hemoglobinuria--molecular mechanism of abnormal hemolysis] Tanpakushitsu Kakusan Koso. 38(14):2333-46. 1993
Nagakura S, Nakakuma H, Horikawa K, Hidaka M, Kagimoto T, Kawakita M, Tomita M, Takatsuki K.: Expression of decay-accelerating factor and CD59 in lymphocyte subsets of healthy individuals and paroxysmal nocturnal hemoglobinuria patients. Am J Hematol. 43(1):14-8. 1993
Nakakuma H, Horikawa K, Hidaka M, Nagakura S, Kawaguchi T, Kawakita M, Kagimoto T, Takatsuki K.: Rare discovery of paroxysmal nocturnal hemoglobinuria patients with B blood group antigen. Int J Hematol. 57(2):187-8. 1993
Hidaka M, Nagakura S, Horikawa K, Kawaguchi T, Iwamoto N, Kagimoto T, Takatsuki K, Nakakuma H.: Impaired glycosylation of glycosylphosphatidylinositol-anchor synthesis in paroxysmal nocturnal hemoglobinuria leucocytes.　Biochem Biophys Res Commun. 191(2):571-9. 1993
Nakakuma H, Horikawa K, Kawaguchi T, Hidaka M, Nagakura S, Hirai S, Kageshita T, Ono T, Kagimoto T, Iwamori M, et al.: Common phenotypic expression of gangliosides GM3 and GD3 in normal human tissues and neoplastic skin lesions.
Jpn J Clin Oncol. 22(5):308-12. 1992
Hidaka M, Nakakuma H, Kawaguchi T, Nagakura S, Horikawa K, Okuno Y, Kagimoto T, Takatsuki K.: Altered expression of protein kinase C in adult T-cell leukemia cells.
Int J Hematol. 56(2):135-41. 1992
Iwamori M, Nakakuma H.: [Alteration in ganglioside of erythrocytes from patients with paroxysmal nocturnal hemoglobinuria] Tanpakushitsu Kakusan Koso. 1992 Aug;37(11 Suppl):1940-4. 1992
Kageshita T, Ono T, Hirai S, Yoshii A, Kimura T, Nakakuma H, Horikawa K, Takatsuki K, Ferrone S.: Ganglioside, adhesion molecule, and HLA antigen expression in basal cell carcinoma lesions. Cancer Res. 52(11):3201-7. 1992
Nakakuma H, Nagakura S, Kawaguchi T, Horikawa K, Kagimoto T, Kawakita M, Tomita M, Takatsuki K.: Increased plasma decay-accelerating factor levels in paroxysmal nocturnal hemoglobinuria. Int J Hematol. 55(2):121-5. 1992
Ikeda T, Nakakuma H, Shionoya H, Kawaguchi T, Yamatsu K, Takatsuki K.: Ganglioside-induced inhibition of in vivo immune response in mice. Life Sci. 51(11):847-51. 1992
Horikawa K, Nakakuma H, Nagakura S, Kawakita M, Kagimoto T, Iwamori M, Nagai Y, Abe T, Takatsuki K.: Hemolysis of human erythrocytes is a new bioactivity of gangliosides. J Exp Med. 174(6):1385-91. 1991
Horikawa K, Yamasaki M, Iwamori M, Nakakuma H, Takatsuki K, Nagai Y.: Concanavalin A-stimulated expression of gangliosides with GalNAc beta 1-4(NeuAc alpha 2-3)Gal beta structure in murine thymocytes. Glycoconj J. 8(4):354-60. 1991
Nakakuma H, Kawaguchi T.: [Altered metabolism of membrane glycosphingolipids in erythrocytes of paroxysmal nocturnal hemoglobinuria] Rinsho Ketsueki. 32(6):606-11. 1991
Kagimoto T, Oda T, Nakakuma H, Kawaguchi T, Hidaka M, Horikawa K, Matsuzaki H, Takatsuki K. : [Serum deoxythymidine kinase activity in adult T-cell leukemia]
Gan To Kagaku Ryoho. 18(1):63-7.1991
Nakakuma H, Kawaguchi T, Takatsuki K.: [Ganglioside as a potential immune modulator: selective CD4-modulation and inhibition of human immunodeficiency virus infection] Seikagaku. 62(8):1044-7.1990
Nakakuma H, Kawaguchi T, Horikawa K, Hidaka M, Yonemura Y, Kawakita M, Kagimoto T, Iwamori M, Nagai Y, Takatsuki K.: Altered expression of gangliosides in erythrocytes of paroxysmal nocturnal hemoglobinuria. J Clin Invest. 85(5):1456-61. 1990
Yonemura Y, Kawakita M, Koito A, Kawaguchi T, Nakakuma H, Kagimoto T, Schichishima T, Terasawa T, Akagaki Y, Inai S.: Paroxysmal nocturnal haemoglobinuria with coexisting deficiency of the ninth component of complement: lack of massive haemolytic attack. Br J Haematol. 74(1):108-13. 1990
Nakakuma H, Arai M, Kawaguchi T, Horikawa K, Hidaka M, Sakamoto K, Iwamori M, Nagai Y, Takatsuki K.: Monoclonal antibody to galactosylceramide: discrimination of structural difference in the ceramide moiety. FEBS Lett. 258(2):230-2. 1989
Kagimoto T, Nakakuma H, Kawaguchi T, Takatsuki K.: [Clinical significance of urine protein and its fraction analysis in biochemical tests] Nippon Rinsho. Dec;48 Suppl:138-40. 1989
Kagimoto T, Nakakuma H, Kawaguchi T, Takatsuki K.: [Clinical significance of serum protein and fraction analysis in biochemical tests] Nippon Rinsho. Dec;48 Suppl:118-22. 1989
Nakakuma H, Kawaguchi T, Koito A, Hattori T, Kagimoto T, Takatsuki K.: Inhibition of human immunodeficiency virus infection of human lymphocytes by gangliosides.
Jpn J Cancer Res. 80(8):702-5. 1989
Nakakuma H, Kawaguchi T, Takatsuki K. : [Glycosphingolipids affect on the functional properties of human lymphocytes--in relation to HIV-infection of lymphocytes] Hum Cell. 2(1):45-50. 1989
Tauber AI, Cox JA, Curnutte JT, Carrol PM, Nakakuma H, Warren B, Gilbert H, Blumberg PM.: Activation of human neutrophil NADPH-oxidase in vitro by the catalytic fragment of protein kinase-C. Biochem Biophys Res Commun. 158(3):884-90. 1989
Kawaguchi T, Nakakuma H, Kagimoto T, Shirono K, Horikawa K, Hidaka M, Iwamori M, Nagai Y, Takatsuki K.: Characteristic mode of action of gangliosides in selective modulation of CD4 on human T lymphocytes. Biochem Biophys Res Commun. 158(3):1050-9. 1989
Blumberg PM, Pettit GR, Warren BS, Szallasi A, Schuman LD, Sharkey NA, Nakakuma H, Dell'Aquila ML, de Vries DJ.: The protein kinase C pathway in tumor promotion. Prog Clin Biol Res. 298:201-12. 1989
Nakakuma H, Willingham MC, Blumberg PM.: Effect of microinjected catalytic fragment of protein kinase C on morphological change in Swiss 3T3 cells. Cancer Commun. 1(2):127-32. 1989
Nakakuma H, Yamakawa A.: [Glycolipids in cell membrane] Nippon Rinsho. 43(4):692-6. 1985
Nakakuma H, Sanai Y, Shiroki K, Nagai Y. Gene-regulated expression of glycolipids: appearance of GD3 ganglioside in rat cells on transfection with transforming gene E1 of human adenovirus type 12 DNA and its transcriptional subunits. J Biochem (Tokyo). 96(5):1471-80. 1984

園木孝志

Nakamura M, Gotoh T, Okuno Y, Tatetsu H, Sonoki T, Uneda S, Mori M, Mitsuya H, Hata H.：Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells. Leuk Lymphoma. 47(3):531-9. 2006
Izumi Taniguchi, Hiroyuki Hata and Takashi Sonoki : Down- regulation of Cyclin D3 by Small- interfering RNA induces Cell Cycle Arrest and Apoptosis through the Dissociation of p27 kip1 in a t ( 6 ; 14) ( p21 ; q32) positive Myeloma Cell Line. Journal of Clinical Experimental Hematopathology 45(2):81-7. 2005
Sonoki T, Iwanaga E, Mitsuya H, Asou N.：Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia. Leukemia.　19(11):2009-10. 2005
Sonoki T, Iwanaga E, Mitsuya H, Asou N.：Ovarian relapse seven years after bone marrow transplantation for B-cell acute lymphoblastic leukemia: an unusual Krukenberg tumor. Am J Hematol. 80(1):75-6. 2005
Tatetsu H, Okuno Y, Nakamura M, Matsuno F, Sonoki T, Taniguchi I, Uneda S, Umezawa K, Mitsuya H, Hata H.：Dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, induces apoptosis in multiple myeloma cells in an IkappaBalpha-independent manner. Mol Cancer Ther. 4(7):1114-20. 2005
Karran EL, Sonoki T, Dyer MJ.：Cloning of immunoglobulin chromosomal translocations by long-distance inverse polymerase chain reaction. Methods Mol Med. 115:217-30. 2005
Sonoki T, Willis TG, Oscier DG, Karran EL, Siebert R, Dyer MJ.：Rapid amplification of immunoglobulin heavy chain switch (IGHS) translocation breakpoints using long-distance inverse PCR. Leukemia. 18(12):2026-31. 2004
Kawakami K, Miyanishi S, Sonoki T, Nakamura S, Nomura K, Taniwaki M, Murata T, Kadowaki S, Kadowaki N, Miura I.：Case of B-cell lymphoma with rearrangement of the BCL1, BCL2, BCL6, and c-MYC genes. Int J Hematol. 79(5):474-9. 2004
Uneda S, Matsuno F, Sonoki T, Tniguchi I, Kawano F, Hata H.：Expressions of vascular endothelial growth factor and angiopoietin-2 in myeloma cells. Haematologica. 88(1):113-5. 2003
Kuppers R, Sonoki T, Satterwhite E, Gesk S, Harder L, Oscier DG, Tucker PW, Dyer MJ, Siebert R.：Lack of somatic hypermutation of IG V(H) genes in lymphoid malignancies with t(2;14)(p13;q32) translocation involving the BCL11A gene. Leukemia. 16(5):937-9.2002
Martin-Subero JI, Gesk S, Harder L, Sonoki T, Tucker PW, Schlegelberger B, Grote W, Novo FJ, Calasanz MJ, Hansmann ML, Dyer MJ, Siebert R.：Recurrent involvement of the REL and BCL11A loci in classical Hodgkin lymphoma. Blood. 99(4):1474-7. 2002
Satterwhite E, Sonoki T, Willis TG, Harder L, Nowak R, Arriola EL, Liu H, Price HP, Gesk S, Steinemann D, Schlegelberger B, Oscier DG, Siebert R, Tucker PW, Dyer MJ.：The BCL11 gene family: involvement of BCL11A in lymphoid malignancies. Blood. 98(12):3413-20. 2001
Sonoki T, Harder L, Horsman DE, Karran L, Taniguchi I, Willis TG, Gesk S, Steinemann D, Zucca E, Schlegelberger B, Sole F, Mungall AJ, Gascoyne RD, Siebert R, Dyer MJ.：Cyclin D3 is a target gene of t(6;14)(p21.1;q32.3) of mature B-cell malignancies.　Blood. 98(9):2837-44. 2001
Sanchez-Izquierdo D, Siebert R, Harder L, Marugan I, Gozzetti A, Price HP, Gesk S, Hernandez-Rivas JM, Benet I, Sole F, Sonoki T, Le Beau MM, Schlegelberger B, Dyer MJ, Garcia-Conde J, Martinez-Climent JA.：Detection of translocations affecting the BCL6 locus in B cell non-Hodgkin's lymphoma by interphase fluorescence in situ hybridization. Leukemia. 15(9):1475-84. 2001
Harada N, Hata H, Matsuno F, Sonoki T, Kuribayashi N, Matsuzaki H, Mitsuya H.：Absence of Kaposi's sarcoma-associated herpesvirus (KSHV) in bone marrow cells from Japanese myeloma patients. Leukemia. 13(9):1465-6.
Sonoki T, Matsuzaki H, Satterwhite E, Nakazawa N, Hata H, Tucker PW, Taniwaki M, Kuribayashi N, Harada N, Matsuno F, Mitsuya H.：A plasma cell leukemia patient showing bialleic 14q translocations: t(2;14) and t(11;14). Acta Haematol.101(4):197-201. 1999
Sonoki T, Matsuzaki H, Nagasaki A, Hata H, Yoshida M, Matsuoka M, Kuribayashi N, Kimura T, Harada N, Takatsuki K, Mitsuya H, Mori M.：Detection of inducible nitric oxide synthase (iNOS) mRNA by RT-PCR in ATL patients and HTLV-I infected cell lines: clinical features and apoptosis by NOS inhibitor. Leukemia. 13(5):713-8. 1999
Kuribayashi N, Hata H, Yoshida M, Sonoki T, Nagasaki A, Kimura T, Harada N, Matsuzaki H.：Establishment and characterization of a CD95 (Fas/Apo-1)-negative myeloma cell line. Acta Haematol. 101(3):113-8. 1999
Sonoki T, Hata H, Kuribayashi N, Yoshida M, Harada N, Nagasaki A, Kimura T, Matsuno F, Mitsuya H, Matsuzaki H.：Expression of PRAD1/cyclin D1 in plasma cell malignancy: incidence and prognostic aspects. Br J Haematol. 104(3):614-7. 1999
Kuribayashi N, Hata H, Matsuzaki H, Yoshida M, Sonoki T, Nagasaki A, Kimura T, Harada N, Takatsuki K.：Establishment of a monoclonal antibody to human myeloma cell: relation to chemotherapy and extramedullar infiltration. Med Oncol. 15(4):248-54. 1998
Sonoki T, Nakazawa N, Hata H, Taniwaki M, Nagasaki A, Seto M, Yoshida M, Kuribayashi N, Kimura T, Harada N, Mitsuya H, Matsuzaki H.：Amplification and overexpression of the PRAD1/Cyclin D1 gene in a multiple myeloma cell line. Int J Hematol. 68(4):459-61. 1998
Mori M, Gotoh T, Nagasaki A, Takiguchi M, Sonoki T. ：Regulation of the urea cycle enzyme genes in nitric oxide synthesis.　J Inherit Metab Dis. 21 Suppl 1:59-71. 1998
Kuribayashi N, Matsuzaki H, Hata H, Yoshida M, Sonoki T, Nagasaki A, Kimura T, Okamoto K, Kurose M, Tsuda H, Takatsuki K.：Multiple myeloma associated with serum amino acid disturbance and high output cardiac failure. Am J Hematol. 57(1):77-81. 1998
Hata H, Matsuzaki H, Yoshida M, Sonoki T, Kuribayashi N, Nagasaki A, Kimura T, Harada N, Takatsuki K.：Hyperdiploid myeloma cell as an indicator of poor prognosis and drug refractoriness. Int J Hematol. 66(2):219-26. 1997
Sonoki T, Nagasaki A, Gotoh T, Takiguchi M, Takeya M, Matsuzaki H, Mori M.：Coinduction of nitric-oxide synthase and arginase I in cultured rat peritoneal macrophages and rat tissues in vivo by lipopolysaccharide. J Biol Chem.272(6):3689-93. 1997
Gotoh T, Sonoki T, Nagasaki A, Terada K, Takiguchi M, Mori M.：Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like cell line. FEBS Lett. 395(2-3):119-22. 1996
Matsuzaki H, Sonoki T.： [Adult T cell leukemia (ATL)] Ryoikibetsu Shokogun Shirizu. (15):135-8. 1996
Sonoki T, Matsuzaki H, Asou N, Hata H, Matsuno F, Yoshida M, Nagasaki A, Kuribayashi N, Kudo H, Takatsuki K.: Aggressive CD5-positive diffuse large B cell lymphoma showing c-myc rearrangements developed in a patient with autoimmune hemolytic anemia. Int J Hematol. 63(1):71-6. 1996
Sonoki T, Matsuzaki H, Miyamoto K, Taniwaki M, Yoshino T, Hata H, Yoshida M, Matsuno F, Nagasaki A, Kuribayashi N, et al.:Establishment of the novel B acute lymphoblastic leukemia (FAB L3) cell line KHM-10B with a 13q34 abnormality and constitutive expression of c-myc and max during cell cycle. Leukemia. 9(12):2093-9. 1995
Hata H, Matsuzaki H, Takeya M, Yoshida M, Sonoki T, Nagasaki A, Kuribayashi N, Kawano F, Takatsuki K.: Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders. Blood. 86(5):1939-45. 1995
Matsuzaki H, Hata H, Sonoki T, Matsuno F, Kuribayashi N, Yoshida M, Nagasaki A, Murata H, Fujiyama S, Takatsuki K.：Serum amino acid disturbance in multiple myeloma with hyperammonemia.　Int J Hematol61(3):131-7. 1995
Hata H, Matsuzaki H, Yoshida M, Matsuno F, Sonoki T, Nagasaki A, Kuribayashi N, Takatsuki K.：Red blood cell volume (MCV) as a new prognostic factor of multiple myeloma.　Eur J Haematol. 54(1):57-8. 1995
Hata H, Matsuzaki H, Sonoki T, Takemoto S, Kuribayashi N, Nagasaki A, Takatsuki K.：Establishment of a CD45-positive immature plasma cell line from an aggressive multiple myeloma with high serum lactate dehydrogenase. Leukemia. 8(10):1768-73. 1994
Hata H, Matsuzaki H, Matsuno F, Sonoki T, Takemoto S, Kuribayashi N, Nagasaki A, Takatsuki K. ：Establishment of a monoclonal antibody to plasma cells: a comparison with CD38 and PCA-1. Clin Exp Immunol. 96(2):370-5. 1994
Hata H, Matsuzaki H, Matsuno F, Yoshida M, Sonoki T, Takemoto S, Takatsuki K.：Expression of fibronectin and adhesion to fibronectin in myeloma cell lines.
Acta Haematol. 89(1):26-31. 1993

花岡伸佳

Tatetsu H, Asou N, Nakamura M, Hanaoka N, Matsuno F, Horikawa K, Mitsuya H.：Torsades de pointes upon fluconazole administration in a patient with acute myeloblastic leukemia. Am J Hematol. 81(5):366-9. 2006
Hanaoka N, Kawaguchi T, Horikawa K, Nagakura S, Mitsuya H, Nakakuma H.：Immunoselection by natural killer cells of PIGA mutant cells missing stress-inducible ULBP. Blood. 107(3):1184-91. 2006