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Department of Oral & Maxillofacial Surgery

Introduction to Department

With its priority on contributing to local medical care, the Department is involved in treatment, research, and education as the central institution for maxillofacial disorders in Wakayama Prefecture. Oromandibular medical treatment is aimed at maintenance and better recovery of functions such as chewing and swallowing.

In terms of research, the Department aims to open the door as widely as possible to proactive research collaborations with other institutions, and carry out solid basic research to resolve issues raised in actual clinical practice.

Research Overview

  1. Basic Research on the Oral Microbiota
    We conduct comprehensive analyses of the oral microbiome, which consists of commensal oral bacteria and fungi, using next-generation sequencing (NGS). Our research focuses on its associations with a variety of diseases, particularly oral mucosal diseases and gastrointestinal disorders.
  2. Research on the Mechanisms of Tooth Development
    Many aspects of tooth development remain to be elucidated. We have been continuously investigating the mechanisms involved, particularly during the crown formation stage, using organ culture of tooth germs and cell culture techniques.
  3. Basic and Clinical Research on Odontogenic Tumors and Cysts
    We also investigate odontogenic tumors and cysts, particularly ameloblastoma, which arise from the process of tooth development. Through elucidation of the mechanisms underlying their characteristic growth within the jawbone, we aim to develop novel therapeutic strategies.
  4. Clinical Research on Jaw Deformities
    Jaw deformities are characterized by craniofacial morphological abnormalities and malocclusion caused by abnormalities in the morphology of the maxilla and mandible and/or in the intermaxillary relationship. Depending on the individual case, orthognathic surgery involving the maxilla, mandible, or both is performed. Although treatment planning is based primarily on morphological considerations, the extent of functional improvement achieved by surgery has not yet been fully clarified. To improve treatment outcomes, we conduct clinical research based on multifaceted preoperative and postoperative evaluations.
  5. Clinical Research on Dysphagia and Articulation Disorders
    Our department treats patients with dysphagia and articulation disorders caused by a variety of factors, including oral cancer treatment and neurological diseases. In addition to oral care, our treatment includes functional rehabilitation using prosthetic devices as well as reconstructive surgery for oral cancer. To improve treatment outcomes, we conduct clinical research, including the evaluation of these therapeutic approaches.