２０１９年　研究業績

【 原著 】

1. T. Tanoue, S. Morita, D. R. Plichta, A. N. Skelly, W. Suda, Y. Sugiura, S. Narushima, H. Vlamakis, I.Motoo, K. Sugita, A. Shiota, K. Takeshita, K. Yasuma, D. Riethmacher, T. Kaisho, J. M. Norman, D. Mucida, M. Suematsu, T. Yaguchi, V. Bucci, T. Inoue, Y. Kawakami, B. Olle, B. Roberts, M. Hattori, R. J. Xavier, K. Atarashi, K. Honda. 2019. A defined commensal consortium induces CD8 T cells and anti-cancer immunity. Nature 565:600-605.
2. T. Orimo, I. Sasaki, H. Hemmi, T. Ozasa, Y. Fukuda-Ohta, T. Ohta, M. Morinaka, M. Kitauchi, T. Yamaguchi, Y. Sato, T. Tanaka, K. Hoshino, K. I. Katayama, S. Fukuda, K. Miyake, M. Yamamoto, T. Satoh, K. Furukawa, E. Kuroda, K. J. Ishii, K. Takeda, T. Kaisho. 2019. Cholera toxin B induces interleukine-1 production from resident peritoneal macrophages through pyrin as well as NLRP3 inflammasome. Int Immunol. 31:657-668. (Selected as 2019 International Immunology Outstanding Merit Award)
3. K. Ikumi, M. Odanaka, H. Shime, M. Imai, S. Osaga, O. Taguchi, E. Nishida, H. Hemmi, T. Kaisho, A. Morita, S. Yamazaki. 2019. Hyperglycemia is associated with psoriatic inflammation in both humans and mice. J Invest Dermatol 139:1329-1338.e7.
4. S. Kimura, N. Kobayashi, Y. Nakamura, T. Kanaya, D. Takahashi, R. Fujiki, M. Mutoh, Y. Obata, T. Iwanaga, T. Nakagawa, N. Kato, S. Sato, T. Kaisho, H. Ohno, K. Hase. 2019. Sox8 is essential for M-cell maturation to accelerate IgA response at the early stage after weaning in mice. J Exp Med 216:831-846.
5. Y. Yamashita, A. Nishikawa, Y. Iwahashi, M. Fujimoto, I. Sasaki, H. Mishima, A. Kinoshita, H. Hemmi, N. Kanazawa, K. Ohshima, K.‑I. Imadome. S.‑i. Murata, K.‑i. Yoshiura, T. Kaisho, T. Sonoki, S. Tamura. 2019. Identification of a novel CCDC22 mutation in a patient with severe Epstein–Barr virus-associated hemophagocytic lymphohistiocytosis and aggressive natural killer cell leukemia. Int J Hematol 109:744-750.
6. T. Yahata, M. Mizoguchi, A. Kimura, T. Orimo, S. Toujima, Y. Kuninaka, M. Nosaka, Y. Ishida, I. Sasaki, Y. Fukuda-Ohta, H. Hemmi, N. Iwahashi, T. Noguchi, T. Kaisho, T. Kondo, K. Ino. 2019. Programmed cell death ligand 1 disruption by clustered regularly interspaced short palindromic repeats/Cas9-genome editing promotes antitumor immunity and suppresses ovarian cacer progression. Cancer Sci.110:1279-1292.
7. Argilaguet. J, Pedragosa. M, Esteve-Codina. A, Riera. G, Vidal. E, Peligero-Cruz. C, Casella. V, Andreu. D, Kaisho. T, Bocharov. G, Ludewig. B, Heath. S, Meyerhans. A. 2019. Systems analysis reveals complex biological processes during virus infection fate decisions. Genome Res. 29:907-919.
8. N. Tsuchiya, R. Zhang, T. Iwama, N. Ueda, T. Liu, M. Tatsumi, Y. Sasaki, R. Shimoda, Y. Osako, Y. Sawada, Y. Kubo, A. Miyashita, S. Fukushima, Z. Cheng, R. Nakaki, K. Takubo, S. Okada, S. Kaneko, H. Ihn, T. Kaisho, Y. Nishimura, S. Senju, I. Endo, T. Nakatsura, Y. Uemura. 2019. Type I interferon delivery by iPSC-derived myeloid cells elicits antitumor immunity via XCR1+ dendritic cells. Cell Rep. 29:162-175.