論文
【原著論文】
1. Koyama AH, Wada C, Nagata T and Yura T: Indirect selection for plasmid mutants: Isolation of ColVBtrp mutants defective in self-maintenance in Escherichia coli. Journal of Bacteriology, 122: 73-79, 1975.
2. Koyama AH and Yura T: Plasmid mutations affecting self-maintenance and host growth in Escherichia coli. Journal of Bacteriology, 122: 80-88, 1975.
3. Koyama AH, Maeda T, Toyama S, Ohnishi S, Uetake H and Toyama S: Interaction between Sendai virus and KB cell lines with altered cell fusion ability: A study employing electron spin resonance. Biochimica et Biophysica Acta, 508: 130-136, 1978.
4. Koyama AH and Toyama S: Revertant analysis of a mutant KB cell (sil cell) line with altered cell fusion capacity. Annual Report of the Institute for Virus Research, Kyoto University, 21: 30-32, 1978.
5. Koyama AH and Toyama S: Role of Sendai virus-receptors in trans-membrane transfer of ricin molecules. Annual Report of the Institute for Virus Research, Kyoto University, 21: 50-53, 1978.
6. Koyama AH and Toyama S: Biochemical characterization of mutant KB cells with altered sensitivity to Sendai virus. Annual Report of the Institute for Virus Research, Kyoto University, 22: 41-44, 1979.
7. Toyama S, Koyama AH and Toyama S: Deficient cytidine monophospho-N-acetylneuraminic acid:glycoprotein sialyltransferase activity in a clone of KB cells with altered cell fusion ability. Journal of Biological Chemistry, 258: 9147-9152, 1983.
8. Koyama AH and Uchida T: Inhibition of multiplication of herpes simplex virus type 1 by ammonium chloride and chloroquine. Virology 138: 332-335, 1984.
9. Magee AI, Koyama AH, Malfer C, Wen D and Schlesinger MJ: Release of fatty acids from virus glycoproteins by hydroxylamine. Biochimica et Biophysica Acta, 798: 156-166, 1984.
10. Schlesinger S, Koyama AH, Malfer C, Gee SL and Schlesinger MJ: The effects of inhibitors of glucosidase I on the formation of Sindbis virus. Virus Research, 2: 139-149, 1985.
11. 馬原文彦、古賀敬一、沢田誠三、谷口哲三、重見文雄、須藤恒久、坪井義昌、大谷明、小山 一、内山恒夫、内田孝宏: わが国初の紅班熱リケッチア感染症. 感染症誌 59: 1165-1172, 1985.
12. Koyama AH and Uchida T: The mode of entry of herpes simplex virus type 1 into Vero cells. Microbiology and Immunology, 31: 123-130, 1987.
13. Koyama AH and Uchida T: Quantitative studies on the maturation process of herpes simplex virus type 1 in Vero cells. Virus Research, 10: 281-286, 1988.
14. Uchida T, Uchiyama T and Koyama AH: Isolation of spotted fever group rickettsiae from humans in Japan. Journal of Infectious Disease, 158: 664-665, 1988.
15. Koyama AH and Uchida T: The effect of ammonium chloride on the multiplication of herpes simplex virus type 1 in Vero cells. Virus Research, 13: 271-282, 1989.
16. Koyama AH and Uchida T: Inhibition by brefeldin A of the envelopment of nucleocapsids in herpes simplex virus type 1-infected Vero cells. Archives of Virology, 135: 305-317, 1994.
17. Baines JD, Koyama AH, Huang T and Roizman B: The UL21 gene products of herpes simplex virus 1 are dispensable for growth in cultured cells. Journal of Virology, 68, 2929-2936, 1994.
18. Koyama AH: Induction of apoptotic DNA fragmentation by the infection of vesicular stomatitis virus. Virus Research, 37: 285-290, 1995.
19. Koyama AH and Miwa Y: Suppression of apoptotic DNA fragmentation in herpes simplex virus type 1-infected cells. Journal of Virology, 71: 2567-2571, 1997.
20. Koyama AH and Adachi A: Induction of apoptosis by herpes simplex virus type 1. Journal of General Virology, 78: 2909-2912, 1997.
21. Koyama AH, Arakawa T and Adachi A: Acceleration of virus-induced apoptosis by tumor necrosis factor. FEBS Letters, 426: 179-182, 1998.
22. Irie H, Koyama AH, Kubo H, Fukuda A, Aita K, Koike T, Yoshimura A, Yoshida T, Shiga J and Hill T: Herpes simplex virus hepatitis in macrophage-depleted mice: the role of massive apoptotic cell death in pathogenesis. Journal of General Virology, 79: 1225-1231, 1998.
23. Koyama AH, Akari H, Adachi A, Goshima F and Nishiyama Y: Induction of apoptosis in HEp-2 cells by the infection with herpes simplex virus type 2. Archives of Virology, 143: 2435-2441, 1998.
24. Akari H, Yamamoto Y, Hiwada H, Saito Y, Takayanagi N, Koyama AH and Adachi A: Suppression of HIV-1 replication in peripheral blood lymphocytes by fasudil. Journal of Medical Investigation, 44: 211-214, 1998.
25. Shimano R, Inubushi R, Amano K, Ogasawara T, Akari H, Koyama AH, Kawamura M and Adachi A: Complete inhibition of SIVmac replication by its capsid mutants. Virus Genes, 17: 43-48, 1998.
26. Tokunaga K, Kojima A, Kurata T, Ikuta K, Akari H, Koyama AH, Kawamura M, Inubushi R, Shimano R and Adachi A: Enhancement of human immunodeficiency virus type 1 infectivity by Nef is producer cell-dependent. Journal of General Virology, 79: 2447-2453, 1998.
27. Fukumori T, Akari H, Iida S, Hata S, Kagawa S, Aida Y, Koyama AH and Adachi A: The HIV-1 Vpr displays strong anti-apoptotic activity. FEBS Letters, 432: 17-20, 1998.
28. Tokunaga K, Kojima A, Kurata T, Ikuta K, Inubushi R, Shimano R, Kawamura M, Akari H, Koyama AH and Adachi A: Producer cell-dependent requirment of the Nef protein for efficient entry of HIV-1 into cells. Biochemical and Biophysical Research Communications, 250: 565-568, 1998.
29. Adachi A, Oshima Y and Koyama AH: Activation of HIV-1 enhancer sequence by vaccinia virus. International Journal of Molecular Medicine, 3: 311-313, 1999.
30. Iida S, Fukumori T, Oshima Y, Akari H, Koyama AH and Adachi A: Compatibility of vpu-like activity in the four groups of primate immunodeficiency virus. Virus genes, 18: 183-187, 1999.
31. Iida S, Fukumori T, Oshima Y, Koyama AH and Adachi A: Growth characteristics of T-cell tropic HIV-1 vpu gene mutants in human peripheral blood mononuclear cells. Journal of Medical Investigation, 46: 43-47, 1999.
32. Akari H, Uchiyama T, Fukumori T, Iida S, Koyama AH and Adachi A: Pseudotyping HIV-1 by vesicular stomatitis virus G protein does not reduce the cell-dependent requirment of Vif for optimal infectivity: functional difference between Vif and Nef. Journal of General Virology, 80: 2945-2949, 1999.
33. Adachi A, Tamaki M, Shimano R, Inubushi R, Naito T, Yoshida K, Oshima Y, Kawamura M and Koyama AH: Cell-dependent replication potentials of HIV-1 gag mutants. Microbes and Infection, 1: 671-676, 1999.
34. Hata S, Koyama AH, Shiota H, Adachi A, Goshima F and Nishiyama Y: Antiapoptotic activity of herpes simplex virus type 2: A role of US3 protein kinase gene. Microbes and Infection, 1: 601-607, 1999.
35. Kurokawa M, Koyama AH, Yasuoka S and Adachi A: Influenza virus overcomes apoptosis by rapid multiplication. International Journal of Molecular Medicine, 3: 527-530, 1999.
36. Koyama AH, Arakawa T and Adachi. A. Comparison of an antiviral activity of recombinant consensus interferon with recombinant interferon-α-2b. Microbes and Infection, 1: 1073-1077, 1999.
37. Koyama AH, Arakawa T and Adachi A. Characterization of apoptosis induced by sorbitol: A unique system for the detection of antiapoptotic activities of viruses. Microbes and Infection, 2: 599-606, 2000.
38. Fukumori T, Akari H, Yoshida A, Fujita M, Koyama AH and Adachi A. Regulation of cell cycle and apoptosis by human immunodeficiency virus type 1Vpr. Microbes and Infection, 2: 1011-1017, 2000.
39. Koyama AH, Irie H, Ueno F, Ogawa M, Nomoto A and Adachi A: Suppression of apoptotic and necrotic cell death by poliovirus. Journal of General Virology, 82: 2965-2972, 2001.
40. Koyama, AH, Ogawa M, Kato A, Nagai Y and Adachi A. Lack of apoptosis in the Sendai virus-infected HEp-2 cells without participation of viral antiapoptosis gene. Microbes and Infection, 3: 1115-1121, 2001.
41. Aita K, Irie H, Koyama AH, Fukuda A, Yoshida T and Shiga J: Acute adrenal infection by HSV-1: Role of apoptosis in viral replication. Archives of Virology, 146: 2009-2020, 2001.
42. Fujita M, Yoshida A, Miyaura M, Sakurai A, Akarai H, Koyama AH and Adachi A: Cyclophilin A-independent replication of human immunodeficiency virus type 1 isolate carrying a small portion of the simian immunodeficiency virus SIVmacgag capsid region. Journal of Virology, 75: 10527-10531, 2001.
43. Adachi A, Miyaura M, Sakurai A, Yoshida A, Koyama AH and Fujita M: Growth characteristics of SHIV without the vpu gene. International Journal of Molecular Medicine, 8: 641-644, 2001.
44. Irie H, Aita K, Koyama AH, Fukuda A, Yoshida T and Shiga J: The role of donnor CD4+ T cells in the reconstitution of oral immunity by HSV-1 in SCID mice. Journal of Infectious Disease, 185: 409-416, 2002.
45. Suzaki Y, Yoshizumi M, Kagami S, Koyama AH, Taketani Y, Houchi H, Tsuchiya K, Takeda E and Tamaki T: Hydrogen peroxide stimulates c-src-mediated big mitogen-activated protein kinase 1 (BMK1) and MEF2C signaling pathway in PC12 cells. Potential role in cell survival following oxidative insults. Journal of Biological Chemistry, 277: 9614-9621, 2002.
46. Fujita M, Sakurai A, Yoshida A, Miyaura M, Koyama AH, Sakai K and Adachi A: Amino acid residues 88 and 89 in the central hydrophilic region of human immunodeficiency virus type 1 Vif are critical for viral infectivity by enhancing the steady-state expression of Vif. Journal of Virology, 77:1626-1632, 2003.
47. Koyama AH, Irie H, Kato A, Nagai Y and Adachi A: Virus multiplication and induction of apoptosis by Sendai virus: Role of the C proteins. Microbes and Infection, 5, 373-378, 2003.
48. Ueno F, Shiota H, Miyaura M, Yoshida A, Sakurai A, Tatsuki J, Koyama AH, Akari H, Adachi A and Fujita M: Vpx and Vpr proteins of HIV-2 up-regulate the viral infectivity by a distinct mechanism in lymphocytic cells. Microbes and Infection, 5, 387-395, 2003.
49. Piroozmand A, Koyama AH, Shimada Y, Fujita M, Arakawa T and Adachi A : Role of Us3 gene of herpes simplex virus type 1 for resistance to interferon. International Journal of Molecular Medicine 14: 631-645, 2004.
50. Uozaki M, Yamasaki H, Katsuyama Y, Higuchi M, Higuti T and Koyama AH: Antiviral effect of octyl gallate against DNA and RNA viruses. Antiviral Research 2006.
【総説】
1. 小山 一: フラクションコレクター ｢蛋白質分解酵素による細胞増殖の開始｣.（総説）蛋白質核酸酵素, 24: 1053, 1979.
2. 小山 一: フラクションコレクター ｢レセプター糖脂質への蛋白質分解酵素の効果?ＭＩＦレセプターはガングリオシド｣.（総説）蛋白質核酸酵素, 24: 1196, 1979.
3. Uchida T, Uchiyama T, Koyama, AH, Yu, XJ, Walker, DH, Funato T and Kitamura Y: Isolation and identification of Rickettsia japonica, causative agent of spotted fever group rickettsial infecteions in Japan. (著書) In Rickettsiae and Rickettsial. Diseases (Proceedings of the.Fourth International Symposium) (J. Kazar & D. Raoult, eds.), Publishing House of the Slovak Academy of Science, Bratislava, pp. 389-395, 1991.
4. 小山 一: フラクションコレクター ｢ウイルスによるトランスフォーメーションの新しい機構｣. (総説) 蛋白質核酸酵素, 37: 1433-1434, 1992.
5. 小山 一: フラクションコレクター ｢トランスフォーメーションにおけるアポトーシス抑制の役割｣. (総説) 蛋白質核酸酵素, 37: 2296-2298, 1992.
6. 小山 一: フラクションコレクター ｢ウイルス感染とアポトーシス｣. (総説) 蛋白質核酸酵素, 38: 1003-1005, 1993.
7. 小山 一: ウイルス感染防御機構としてのアポトーシス. (総説) 蛋白質核酸酵素, 41: 1363-1371, 1996.
8. 小山 一: フラクションコレクター ｢エイズ発症におけるアポトーシスの役割｣. (総説) 蛋白質核酸酵素, 41: 1438-1439, 1997.
9. Inubushi R, Tamaki M, Shimano R, Koyama AH, Akari H and Adachi A: Functional roles of HIV accessory proteins for viral replication. (総説) International Journal of Molecular Medicine, 2: 429-433, 1998.
10. Koyama AH, Irie H, Fukumori T, Hata S, Iida S, Akari H and Adachi A: Role of virus-induced apoptosis in a host defense mechanism against virus infection. (総説) Journal of Medical Investigation, 45: 37-45, 1998.
11. Shimano R, Inubushi R, Tamaki M, Akari H, Koyama AH and Adachi A: The non-env tropism of HIV/SIV. (総説) International Journal of Molecular Medicine, 2: 541-544, 1998.
12. Adachi A, Iida S, Fukumori T, Tamaki M, Inubushi R, Shimano R, Oshima Y, Akari H and Koyama AH: Exchangeability of accessory Vif and Vpu proteins between various HIV/SIVs. (総説) International Journal of Molecular Medicine, 3: 193-197, 1999.
13. Fukumori T, Kagawa S, Iida S, Oshima Y, Akari H, Koyama AH and Adachi A: Rev-dependent expression of three species of HIV-1 mRNAs. (総説) International Journal of Molecular Medicine, 3: 297-302, 1999.
14. Koyama AH, Fukumori T, Fujita M, Irie H and Adachi A: Physiological significance of apoptosis in animal virus infection. (総説) Microbes and Infection, 2: 1111-1117, 2000.
15. Miyaura M, Yoshida A, Sakurai A, Fujita M, Koyama AH and Adachi A: Mutational analysis of HIV-1 Gag proteins. (総説) International Journal of Molecular Medicine, 6: 265-269, 2000.
16. 小山 一: フラクションコレクター ｢センダイウイルスによるアポトーシス誘導の機構｣. (総説) 蛋白質核酸酵素, 45: 2537-2538, 2000.
17. 小山 一: フラクションコレクター ｢ウイルス感染に伴うアポトーシス誘導の機構 -水疱性口内炎ウイルスのもつアポトーシス誘導蛋白質は複数か？-｣. (総説) 蛋白質核酸酵素, 47: 272-273, 2002.
18. 小山 一: フラクションコレクター ｢HIVによるネクローシスの誘導 -ヘルパーTリンパ球の減少はネクローシスによる感染細胞死か？-｣. (総説) 蛋白質核酸酵素, 47: 1856-1857, 2002.
19. Koyama AH, Adachi A and Irie H: Physiological significance of apoptosis during animal virus infection.（総説） International Reviews of Immunology, 22, 341-359, 2003.
20. Irie H, Aita K, and Koyama AH : A Role for Apoptosis Induced by Acute Herpes Simplex Virus Infection in Mice. （総説）In : International Reviews of Immunology, vol. 23, edited by Blaho JA, Taylor & Francis, Philadelphia, pp. 173-185, 2004.
21. 小山一 ウイルス感染におけるApoptosisとNecrosisの生理的意義. . (総説) 和歌山医学 56: 40-44, 2005
22. 山崎尚, 魚崎操, 入江宏, 小山一 HSV感染とアポトーシス. . (総説) 日本臨床 64: suppl 3, 167-170, 2006
【その他】
1. 小山 一: 単純ヘルペスウイルス感染細胞におけるウイルス粒子形成過程の解析. (その他) 昭和63年度?平成2年度科学研究費補助金（一般研究C: 研究課題番号01570255）研究成果報告書, 1991
2. 小山 一: 今月の Key Words ｢アポトーシスとプログラムされた細胞死｣. (その他) 蛋白質核酸酵素, 41: 1396-1397, 1996.
3. 小山 一、足立 昭夫: Progress in Medicine ｢ＴＮＦによるアポトーシス誘導の加速｣. (その他) Molecular Medicine, 35: 373-374, 1998.
4. 小山 一: ウイルス感染細胞に誘導されるアポトーシスについてのウイルス学的研究. (その他) 平成11年度?平成12年度科学研究費補助金（基盤研究(C)(2): 研究課題番号11670298）研究成果報告書, 2001.
5. 医学書院医学大辞典（伊藤正男、井村裕夫、高久史麿編）「水痘ウイルス、水痘ヘルペス、水痘・帯状疱疹ウイルス、単純ヘルペスウイルス、単純ヘルペス様ウイルス、テグメント蛋白、Bウイルス、ヒト向Bリンパ球性ウイルス、ヒトヘルペスウイルス」項目分担執筆, 2003.
6. 小山 一：ウイルス感染症．「管理栄養士講座 感染と生体防御」森口 覚，酒井 徹，山本 茂編著，建帛社, 東京 pp. 125-150，2004.