過去5年の論文

2009年度

Arakawa T,Kita Y,Koyama AH:Synergistic virus inactivation effects of arginine.
Biotechnol J. 2009 Feb;(2):174-8.

Naito T, Irie H, Tsujimoto K, Ikeda K, Arakawa T and Koyama AH:
Antiviral effect of arginine against herpes simplex virus type 1.
International Journal of Molecular Medicine 23:495-499, 2009.

Utsunomiya H, Ichinose M, Tsujimoto K, Katsuyama Y, Yamasaki H
and Koyama AH, Ejima D and Arakawa T: Co-operative thermal inactivation of human herpes simplex virus and influenza virus by arginine and NaCl.International Journal of Pharmaceutics 366 : 99-102, 2009.

2008年度

Katsuyama Y, Yamasaki H, Tsujimoto K, Koyama AH, Ejima D and
Arakawa T: Butyroyl-arginine as a potent virus inactivation agent.
International Journal of Pharmaceutics 361: 92-98, 2008.

Furuya A, Uozaki M, Yamasaki H, Arakawa T, Arita M and Koyama
AH: Antiviral effects of ascorbic and dehydroascorbic acids in vitro.
International Journal of Molecular Medicine 22: 541-545, 2008.

Murayama M, Tujimoto K, Uozaki M, Katsuyama Y, Yamasaki H, Utsunomiya H, and Koyama AH: Effect of caffeine on the multiplication of DNA and RNA viruses. Molecular Medicine Reports 1: 251-255, 2008.

Yamasaki H, Tsujimoto K, Koyama AH, Ejima D and Arakawa T: Arginine facilitates inactivation of enveloped viruses. Journal of Pharmaceutical Sciences 97: 3067-3073, 2008.

Arakawa T, Kita Y and Koyama AH: Solubility enhancement of gluten and organic compounds by arginine. International Journal of Pharmaceutics. (in press)

Utsunomiya, H., Ichinose M., Uozaki, M., Tsujimoto, K., Yamasaki, H., and Koyama, AH., Antiviral activities of coffee extracts in vitro. Food and Chemical Toxicology 46: 1919-1924, 2008

2007年度
Yamasaki, H., Uozaki, M., Katsuyama, Y., Utsunomiya, T., Arakawa, T., Higuchi, M., Higuti, T., and Koyama, A.H., Antiviral effect of octyl gallate against influenza and other RNA viruses. International Journal of Molecular Medicine 19: 685-688, 2007

Uozaki, M., Yamasaki, H., Katsuyama, Y., Higuchi, M., Higuchi, T., and Koyama, A.H., Antiviral effect of octyl gallate against DNA and RNA viruses. Antiviral Research 45: 32-40, 2007　

2006年度

2005年度
小山一ウイルス感染におけるApoptosisとNecrosisの生理的意義. 和歌山医学 56: 40-44, 2005

山崎尚, 魚崎操, 入江宏, 小山一 HSV感染とアポトーシス. 日本臨床64,増刊3:167-170,2005

2004 年度
Piroozmand, A., Koyama, A.H., Shimada, Y., Fujita, M., Arakawa, T., and Adachi, A. Role of Us3 gene of herpes simplex virus type 1 for resistance to interferon. International Journal of Molecular Medicine 14: 641-645, 2004.

Irie, H., Aita, K., and Koyama, A.H. A role for apoptosis induced by acute herpes simplex virus infection in mice. International Reviews of Immunology 23: 173-185, 2004.

2003　年度
Ueno, F., Shiota, H., Miyaura, M., Yoshida, A., Sakurai, A., Tatsuki, J., Koyama, A.H., Akari, H., Adachi, A., and Fujita, M. Vpx and Vpr proteins of HIV-2 up-regulate the viral infectivity by a distinct mechanism in lymphocytic cells. Microbes and Infection, 5, 387-395, 2003.

Koyama, A.H., Irie, H., Kato, A., Nagai, Y. and Adachi, A. Virus multiplication and induction of apoptosis by Sendai virus: Role of the C proteins. Microbes and Infection 5: 373-378, 2003.

Koyama, A.H., Adachi, A. and Irie, H. Physiological significance of apoptosis during animal virus infection. International Reviews of Immunology 22: 341-359, 2003.

Fujita, M., Sakurai, A., Yoshida, A., Miyaura, M., Koyama, A.H., Sakai, K., and Adachi, A. Amino acid residues 88 and 89 in the central hydrophilic region of human immunodeficiency virus type 1 Vif are critical for viral infectivity by enhancing the steady-state expression of Vif. Journal of Virology, 77: 1626-1632, 2003.

2002 年度
Irie, H., Aita, K., Koyama, A.H., Fukuda, A., Yoshida, T. and Shiga, J. The role of donnor CD4+ T cells in the reconstitution of oral immunity by herpes simplex virus type 1 in severe combined immunodeficiency mice mice. Journal of Infectious Diseases 185: 409-416, 2002.

Suzaki, Y., Yoshizumi, M., Kagami, S., Koyama, A.H., Taketani, Y., Houchi, H., Tsuchiya, K., Takeda, E. and Tamaki, T. Hydrogen peroxide stimulates c-Src-mediated big mitogen- activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells. Potential role in cell survival following oxidative insults. Journal of Biological Chemistry 277: 9614-9621, 2002.

Nakamura, M., Yang, Q., Ozaki, T., Nakamura, Y., Yamasaki, H. Mori, I. and Kakudo, K. Induction of uPA but not NF-IL3A by Calcitonin is dependent on Erk1/2 Phosphorylation in porcine renal cell line LLC-PK1. Biochemical and Biophysical Research Communications 290: 1483-1488, 2002.

2001 年度
Koyama, A.H., Irie, H., Ueno, F., Ogawa, M., Nomoto, A. and Adachi, A. Suppression of apoptotic and necrotic cell death by poliovirus. Journal of General Virology 82: 2965-2972, 2001.

Koyama, A.H., Ogawa, M., Kato, A., Nagai, Y. and Adachi, A. Lack of apoptosis in the Sendai virus-infected HEp-2 cells without participation of viral antiapoptosis gene. Microbes and Infection 3: 1115-1121, 2001.

Aita, K, Irie, H., Koyama, A.H., Fukuda, A., Yoshida, T. and Shiga, J. Acute adrenal infection by HSV-1: Role of apoptosis in viral replication. Archives of Virology 146: 2009-2020, 2001.

Fujita, M., Yoshida, A., Miyaura, M., Sakurai, A., Akari, H., Koyama, A.H., and Adachi, A. Cyclophilin A-independent replication of human immunodeficiency virus type 1 isolate carrying a small portion of the simian immunodeficiency virus SIVmacgag capsid region. Journal of Virology, 75: 10527-10531, 2001

Segawa, S., Utsunomiya, H., Nakamura, M., Shan, L., Ozaki, T., Mori, I., Yamasaki, H., Taniguchi, T. and Kakudo, K. Sertoli- Leydig cell tumor-immunohistochemical analysis helps exploring tumor characterization. Wakayama Medical Reports 41: 23-27, 2001